Maternal Floor Infarction Wikipedia

Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence.

Maternal floor infarction wikipedia.

It is moot whether such a lesion which i will call true maternal floor infarction occurs but the term maternal floor infarction is not usually used in this sense. A placental infarction results from the interruption of blood supply to a part of the placenta causing its cells to die. To understand the lesion the conditions in which perivillous fibrinoid forms must also be understood. Organization dedicated to.

In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and recurrence are assessed. Small placental infarcts especially at the edge of the placental disc are considered to be normal at term large placental infarcts are associated with vascular abnormalities e g. Placenta maternal floor infarction. Micrograph of a placental infarct.

This website is intended for pathologists and laboratory personnel but not for patients. A maternal floor infarction then should show fibrin or matrix thickening of the maternal surface with otherwise typical changes of infarction in the villi. The pathology is a diffuse increase in peri inter villous fibrinoid and usually with some intervillous thrombi. A pathologic entity characterised by deposition of fibrinoid material in the maternal surface and intervillous spaces of the placenta and which is associated with significant perinatal morbidity and mortality including stillbirth recurrent pregnancy loss premature delivery intrauterine growth restriction and.

The disorder is somewhat misnamed because it is characterized by heavy deposition of fibrin in the decidua beneath the placenta rather than by arterial occlusion. By now everyone agrees that maternal floor infarction is a misnomer at least for most of the cases so labeled. Maternal floor infarction abbreviated mfi is a pathology of the placenta. Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe.

It is formally known as placental maternal floor infarction it is also known as massive perivillous fibrin deposition.