Mesenchymal Stem Cell Therapy For Psoriasis

Psoriasis is a chronic relapsing inflammatory disease affecting 2 3 of the population and is considered to be a systemic disease rather than one limited to the skin.

Mesenchymal stem cell therapy for psoriasis.

Psoriasis is an incurable immune mediated disease which affects approximately 2 of the world s population. For this reason they are currently under investigation in clinical trials for the treatment of several autoimmune systemic disorders. 1 here we report 2 cases of psoriasis vulgaris treated by umbilical cord derived mesenchymal stem cells uc mscs. Current treatments including newly emerged biologic agents have some limitations.

The skin at each of these sites is different and requires different treatments. However there is potential for other stem cell types to help with psoriasis as well. Nowadays mesenchymal stem cell mscs based therapy has become a promising therapeutic field which is expected to help in the treatment of the most costly and incurable diseases. The most common form plaque psoriasis appears most often as red scaly patches that itch and bleed.

Mesenchymal stem cells mscs have recently been shown to have not only regenerative capabilities but also immunomodulating properties. Treatment of psoriasis with mesenchymal stem cells to the editor. Mesenchymal stem cells mscs have recently been shown to have not only regenerative capabilities but also immunomodulating properties. Current treatments including newly emerged biologic agents have some limitations 1 here we report 2 cases of psoriasis vulgaris treated by umbilical cord derived mesen.

Here we explored the feasibility of using human umbilical cord derived msc huc msc infusion as a. For this reason they are currently under investigation in clinical trials for the treatment of several autoimmune systemic disorders. Literature with regard to msc based strategies for the treatment of psoriasis. Indeed according to the researchers psoriasis patients who have undergone bone marrow stem cells transplants have also gone.

Human mesenchymal stem cell therapy stem cells inter. But their contribution to psoriasis and the underlying mechanisms involved remains elusive. Psoriasis can occur on any part of the body eyelids ears mouth and lips skin folds hands and feet arms and legs torso and nails. Psoriasis is a systemic immun.

2 the pathogenesis of psoriasis has an immunological basis. 1 the treatment varies depending on disease severity from topical agents and phototherapy to conventional immunosuppressant drugs and biologic agents. In these 2 cases both of the patients remained relapse free for 4 or 5 years.